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Results for "

macrolide antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (59) ADC Cytotoxin (1) Apoptosis (5) ATP Synthase (1) Autophagy (4) Bacterial (46) CDK (1) Cytochrome P450 (1) DNA/RNA Synthesis (8) Endogenous Metabolite (1) Fungal (11) Isotope-Labeled Compounds (3) Na+/K+ ATPase (1) NF-κB (2) P-glycoprotein (1) Parasite (7) Proton Pump (2)
By Research Areas:	Cancer (19) Infection (60) Inflammation/Immunology (6)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106681

Lagosin Fungichromin; Pentamycin; Cogomycin	Antibiotic Fungal	Cancer
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .

HY-B0643

Dirithromycin 1 Publications Verification LY237216	Bacterial Antibiotic	Infection
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .

HY-126479

Carbomycin B

Magnamycin B
Antibiotic Infection Inflammation/Immunology

Carbomycin B is a macrolide antibiotic .

Carbomycin B Magnamycin B	Antibiotic	Infection Inflammation/Immunology
Carbomycin B is a macrolide antibiotic .

HY-N6783

Oligomycin C	Fungal Antibiotic	Infection
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .

HY-N8386

Berkeleylactone F

Antibiotic Infection Cancer

Berkeleylactone F is an antibiotic macrolide compound. Berkeleylactone F showed modest inhibition of CCRF-CEM leukemia cells .

Berkeleylactone F	Antibiotic	Infection Cancer
Berkeleylactone F is an antibiotic macrolide compound. Berkeleylactone F showed modest inhibition of CCRF-CEM leukemia cells .

HY-128423

Tylvalosin tartrate Acetylisovaleryltylosin tartrate	Antibiotic Bacterial NF-κB Apoptosis	Infection Inflammation/Immunology
Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide *antibiotic* with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .

HY-103250

PF-945863

Antibiotic Infection

PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains .

PF-945863	Antibiotic	Infection
PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains .

HY-125652

Macrosphelide A	Antibiotic	Infection
Macrosphelide A is a macrolide *antibiotic. Macrosphelide A inhibits growth of some ascomycetes, basidiomycetes, oomycetes and all four Gram-positive bacteria tested, including the medically important Staphylococcus aureus* with a MIC of ≤500 μg/mL .

HY-112661

PC-766B antibiotic PC-766B	Antibiotic Bacterial Fungal	Infection Cancer
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na ⁺, K ⁺-ATPase .

HY-N8381

Berkeleylactone E

Antibiotic Infection

Berkeleylactone E is a macrolide antibiotic .
HY-N7141

Spiramycin I

Parasite Antibiotic Bacterial Infection

Spiramycin I is a macrolide antibiotic and antiparasitic .
HY-A0071

Tildipirosin

Bacterial Antibiotic Infection

Tildipirosin, a long-acting macrolide, has antibiotic activity.

Berkeleylactone E	Antibiotic	Infection
Berkeleylactone E is a macrolide antibiotic .

Spiramycin I	Parasite Antibiotic Bacterial	Infection
Spiramycin I is a macrolide *antibiotic* and antiparasitic .

Tildipirosin	Bacterial Antibiotic	Infection
Tildipirosin, a long-acting macrolide, has antibiotic activity.

HY-17506

Azithromycin 20+ Cited Publications CP 62993	Bacterial Autophagy Antibiotic Parasite	Infection Cancer
Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

HY-B0435

Roxithromycin

4 Publications Verification

RU-28965
Bacterial Antibiotic Infection

Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

Roxithromycin 4 Publications Verification RU-28965	Bacterial Antibiotic	Infection
Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-17506A

Azithromycin hydrate 20+ Cited Publications CP-62993 dihydrate	Bacterial Autophagy Antibiotic Parasite	Infection Cancer
Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

HY-136652

Platenomycin A1

YL-704 A1
Antibiotic Infection

Platenomycin A1 (compound 1) is a macrolide antibiotic .
HY-107213

Tulathromycin B

CP 547272
Antibiotic Bacterial Infection

Tulathromycin B (CP 547272) is an isomer of Tulathromycin (a macrolide antibiotic) .

Platenomycin A1 YL-704 A1	Antibiotic	Infection
Platenomycin A1 (compound 1) is a macrolide antibiotic .

Tulathromycin B CP 547272	Antibiotic Bacterial	Infection
Tulathromycin B (CP 547272) is an isomer of Tulathromycin (a macrolide antibiotic) .

HY-B1908

Midecamycin 2 Publications Verification SF-837; antibiotic SF-837	Bacterial Antibiotic	Infection
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.

HY-116010

Oleandomycin 1 Publications Verification	Bacterial Antibiotic	Infection
Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity.

HY-122207

Erythromycin A enol ether

Others Infection

Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect .

Erythromycin A enol ether	Others	Infection
Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect .

HY-B0905

Tilmicosin 2 Publications Verification LY-177370; EL-870	Bacterial Antibiotic	Infection
Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.

HY-125707

Concanamycin B

MCH 210
Proton Pump Antibiotic Infection

Concanamycin B is a macrolide antibiotic, which can inhibit the cavitation type H+-ATPases, and the IC₅₀ value is 5 nM .

Concanamycin B MCH 210	Proton Pump Antibiotic	Infection
Concanamycin B is a macrolide antibiotic, which can inhibit the cavitation type H+-ATPases, and the IC₅₀ value is 5 nM .

HY-N7112

Leucomycin Kitasamycin	Bacterial Antibiotic	Infection
Leucomycin (kitasamycin) is a macrolide antibiotic produced by Streptomyces kitasatoensis with broad-spectrum antibacterial activity .

HY-W055872

Erythromycylamine	Antibiotic	Infection
Erythromycylamine is a macrolide antibiotic. Erythromycylamine has antibacterial activity against most Gram-positive cocci and M. catarrhalis .

HY-B0220S3

Erythromycin-13C2

Bacterial Infection

Erythromycin- ¹³C₂ is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections .

Erythromycin-13C2	Bacterial	Infection
Erythromycin- ¹³C₂ is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections .

HY-108881

Troleandomycin Triacetyloleandomycin	Cytochrome P450 Bacterial	Infection Inflammation/Immunology
Troleandomycin (Triacetyloleandomycin), a macrolide acrolide antibiotic, is a selective CYP3A inhibitor. Troleandomycin is an oral corticosteroid for asthma study .

HY-124138

Pikromycin Albomycetin; Amaromycin	Antibiotic Bacterial	Infection
Pikromycin is a macrolide antibiotic that has been found in S. venezuelae and active against E. coli, S. aureus and B. subtilis .

HY-A0062

Telithromycin 5 Publications Verification HMR3647; RU66647	Bacterial Antibiotic	Infection Inflammation/Immunology
Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .

HY-N1724

Concanamycin A 5+ Cited Publications antibiotic X 4357B; Folimycin; X 4357B
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide *antibiotic, a vacuolar type H ⁺-ATPase (V-ATPase)* inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research ^- .

HY-B1920

Josamycin EN-141	Bacterial Antibiotic	Infection
Josamycin (EN-141) is a macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant K_d from ribosome for Josamycin is 5.5 nM.

HY-17506S

Azithromycin-d3	Bacterial Autophagy Antibiotic	Infection Cancer
Azithromycin-d₃ is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].

HY-N6738

Bafilomycin B1	Bacterial Fungal Antibiotic	Infection
Bafilomycin B1 is a macrolide antibiotic isolated from Streptomyces sp, inhibits Gram-positive bacteria and fungi, and acts as an inhibitor of K ⁺-dependent ATPase of E. coli .

HY-B0905S

Tilmicosin-d3 LY-177370-d₃; EL-870-d₃	Bacterial Antibiotic	Infection
Tilmicosin-d₃ is the deuterium labeled Tilmicosin. Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.

HY-B1921

Miocamycin Midecamycin acetate; Ponsinomycin
Miocamycin (Midecamycin acetate) is a derivative of midecamycin (HY-B1908), a macrolide antibiotic that can be isolated from a culture broth of Streptomyces mycarofaciens. Miocamycin has antibacterial properties .

HY-N12654

Irumamycin	Fungal Parasite Antibiotic	Infection
Irumamycin is a natural 20-membered macrolide *antibiotic*. Irumamycin is active in vitro against some phytopathogenic fungi . Irumamycin also shows potent antitrypanosomal activity .

HY-126906

Milbemycin A4	Antibiotic P-glycoprotein	Cancer
Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity sup>[2].

HY-125637

Venturicidin B Aabomycin A2	Fungal ATP Synthase	Infection
Venturicidin B (Aabomycin A2) is a macrolide antibiotic isolated from Streptomyces sp., used as an antifungal agent, a potent inhibitor of the mitochondrial F0-ATP synthase complex .

HY-B0435S

Roxithromycin-d7 RU-28965-d₇	Isotope-Labeled Compounds	Others
Roxithromycin-d₇ (RU-28965-d₇)is the deuterium labeledRoxithromycin(HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-15662

Tulathromycin A 1 Publications Verification Tulathromycin; CP 472295	Antibiotic Bacterial	Infection
Tulathromycin A (Tulathromycin), a macrolide *antibiotic, inhibits protein synthesis* (IC₅₀=0.26 µM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .

HY-N6718

Filipin III 2 Publications Verification	Fungal	Inflammation/Immunology
Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure .

HY-100593

Spiramycin 1 Publications Verification Rovamycin	Bacterial Parasite Antibiotic	Infection
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached .

HY-B0133

Natamycin 5 Publications Verification Pimaricin	Fungal Endogenous Metabolite Antibiotic Bacterial	Infection
Natamycin (Pimaricin) is a macrolide *antibiotic* agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-161300

Antibacterial agent 191	Bacterial Antibiotic	Infection
Antibacterial agent 191 (compound 11a) is a potent semi-synthetic antibiotic. Antibacterial agent 191 exhibits preferable metabolic stability .

HY-N7121

Erythromycin estolate 1 Publications Verification	Bacterial	Infection
Erythromycin estolate, erythromycin derivative , is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin estolate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin estolate toxicity is related to its inhibitory effect on bile acid transport .

HY-133537

Hygrolidin	Antibiotic Fungal ADC Cytotoxin	Infection Cancer
Hygrolidin is a 16-membered macrolide *antibiotic* produced by Streptomyces hygroscopicus D-1166. Hygrolidin has *anti-fungus* activity against Valsa ceratosperma. Hygrolidin induces p21 expression and abrogates cell cycle progression at G1 and S phases. Hygrolidin has antitumor activity .

HY-128423A

Tylvalosin Acetylisovaleryltylosin	Antibiotic Bacterial NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Tylvalosin (Acetylisovaleryltylo?sin) is an orally active, broad-spectrum macrolide *antibiotic* with antimicrobial activity. Tylvalosin is an antiviral agent used to study PRRSV infection. Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, alleviates oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .

HY-B0519A

Tylosin 1 Publications Verification Tylosin A	Bacterial Antibiotic	Infection
Tylosin (Tylosin A) is a macrolide *antibiotic* found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519B

Tylosin phosphate 1 Publications Verification	Bacterial Antibiotic	Infection
Tylosin phosphate is a macrolide *antibiotic* found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0220S

Erythromycin-d6	Bacterial Antibiotic	Infection
Erythromycin-d₆ is the deuterium labeled Erythromycin. Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].

HY-B0220

Erythromycin 15+ Cited Publications	Bacterial Antibiotic DNA/RNA Synthesis	Infection Cancer
Erythromycin is a macrolide *antibiotic* produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-106681

Lagosin Fungichromin; Pentamycin; Cogomycin	Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields Cancer	Antibiotic Fungal
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .

HY-126479

Carbomycin B

Magnamycin B
Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification

Antibiotic

Carbomycin B is a macrolide antibiotic .

HY-N6783

Oligomycin C	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields	Fungal Antibiotic
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .

HY-N8386

Berkeleylactone F	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Antibiotic
Berkeleylactone F is an antibiotic macrolide compound. Berkeleylactone F showed modest inhibition of CCRF-CEM leukemia cells .

HY-125652

Macrosphelide A	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Antibiotic
Macrosphelide A is a macrolide *antibiotic. Macrosphelide A inhibits growth of some ascomycetes, basidiomycetes, oomycetes and all four Gram-positive bacteria tested, including the medically important Staphylococcus aureus* with a MIC of ≤500 μg/mL .

HY-112661

PC-766B antibiotic PC-766B	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Fields Cancer	Antibiotic Bacterial Fungal
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na ⁺, K ⁺-ATPase .

HY-N8381

Berkeleylactone E

Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification

Antibiotic

Berkeleylactone E is a macrolide antibiotic .

HY-N7141

Spiramycin I	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Anti-parasitic Disease Research Disease Research Fields	Parasite Antibiotic Bacterial
Spiramycin I is a macrolide *antibiotic* and antiparasitic .

HY-B1908

Midecamycin 2 Publications Verification SF-837; antibiotic SF-837	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.

HY-125707

Concanamycin B MCH 210	Structural Classification Natural Products Microorganisms Source classification	Proton Pump Antibiotic
Concanamycin B is a macrolide antibiotic, which can inhibit the cavitation type H+-ATPases, and the IC₅₀ value is 5 nM .

HY-N7112

Leucomycin Kitasamycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Leucomycin (kitasamycin) is a macrolide antibiotic produced by Streptomyces kitasatoensis with broad-spectrum antibacterial activity .

HY-B1920

Josamycin EN-141	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Josamycin (EN-141) is a macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant K_d from ribosome for Josamycin is 5.5 nM.

HY-N6738

Bafilomycin B1	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Fungal Antibiotic
Bafilomycin B1 is a macrolide antibiotic isolated from Streptomyces sp, inhibits Gram-positive bacteria and fungi, and acts as an inhibitor of K ⁺-dependent ATPase of E. coli .

HY-N12654

Irumamycin	Structural Classification Microorganisms Antibiotics Source classification	Fungal Parasite Antibiotic
Irumamycin is a natural 20-membered macrolide *antibiotic*. Irumamycin is active in vitro against some phytopathogenic fungi . Irumamycin also shows potent antitrypanosomal activity .

HY-N6718

Filipin III 2 Publications Verification	Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Inflammation/Immunology Disease Research Fields Other Antibiotics	Fungal
Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure .

HY-100593

Spiramycin 1 Publications Verification Rovamycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Anti-parasitic Antibacterial Disease Research Disease Research Fields	Bacterial Parasite Antibiotic
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached .

HY-B0133

Natamycin 5 Publications Verification Pimaricin	Structural Classification Preservatives Anti-inflammation/Immunoregulatory Antifungal Classification of Application Fields Source classification Disease Research Endogenous metabolite Food Research Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Fields	Fungal Endogenous Metabolite Antibiotic Bacterial
Natamycin (Pimaricin) is a macrolide *antibiotic* agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-N7121

Erythromycin estolate 1 Publications Verification	Infection Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial
Erythromycin estolate, erythromycin derivative , is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin estolate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin estolate toxicity is related to its inhibitory effect on bile acid transport .

HY-133537

Hygrolidin	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields	Antibiotic Fungal ADC Cytotoxin
Hygrolidin is a 16-membered macrolide *antibiotic* produced by Streptomyces hygroscopicus D-1166. Hygrolidin has *anti-fungus* activity against Valsa ceratosperma. Hygrolidin induces p21 expression and abrogates cell cycle progression at G1 and S phases. Hygrolidin has antitumor activity .

HY-B0519A

Tylosin 1 Publications Verification Tylosin A	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin (Tylosin A) is a macrolide *antibiotic* found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0519B

Tylosin phosphate 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin phosphate is a macrolide *antibiotic* found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0220

Erythromycin 15+ Cited Publications	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields	Bacterial Antibiotic DNA/RNA Synthesis
Erythromycin is a macrolide *antibiotic* produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

HY-B0519

Tylosin tartrate 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Tylosin tartrate is a macrolide *antibiotic* found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-N6716

Filipin complex 5+ Cited Publications	Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Other Diseases Antiviral Disease Research Disease Research Fields Other Antibiotics	Fungal Antibiotic
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I .

HY-130173

Bafilomycin C1	Infection Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Antibacterial Disease Research Anticancer Disease Research Fields Cancer	Bacterial Fungal Na+/K+ ATPase Apoptosis Antibiotic
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H ⁺-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .

HY-N8493

Mycalolide B	Alkaloids Structural Classification Classification of Application Fields Animals Other Alkaloids Source classification Other Diseases Disease Research Fields	Antibiotic
Mycalolide-B is a specific inhibitor of actomyosin ATPase isolated from marine sponge. Mycalolide-B inhibits ATP-induced contraction and Mg ²⁺-ATPase activity in the absence of Ca ²⁺ .

HY-B0220D

Erythromycin thiocyanate	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Anticancer Disease Research Fields	Bacterial Antibiotic DNA/RNA Synthesis
Erythromycin thiocyanate is a macrolide *antibiotic* produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin thiocyanate also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

HY-100558

Bafilomycin A1 Maximum Cited Publications 369 Publications Verification BafA1	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields	Proton Pump Autophagy Antibiotic Bacterial Apoptosis
Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H ⁺-ATPase (V-ATPase) with IC₅₀ values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .

HY-N7454

Anhydroerythromycin A	Infection Structural Classification Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Endogenous metabolite Disease Research Fields	Antibiotic Bacterial
Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.

HY-B0220R

Erythromycin (Standard)	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Fields	Bacterial Antibiotic DNA/RNA Synthesis
Erythromycin (Standard) is the analytical standard of Erythromycin. This product is intended for research and analytical applications. Erythromycin is a macrolide *antibiotic* produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

HY-N6742

Borrelidin 1 Publications Verification Treponemycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Anti-parasitic Antibacterial Disease Research Disease Research Fields	CDK Parasite Apoptosis Antibiotic
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei . Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC₅₀ of 24 μM . Borrelidin is a potent angiogenesis inhibitor, with an IC₅₀ of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells . Borrelidin has strong antimalarial activities, with IC₅₀s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively .

Cat. No.	Product Name	Chemical Structure

HY-17506S

Azithromycin-d3
Azithromycin-d₃ is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].

HY-B0435S

Roxithromycin-d7

Roxithromycin-d₇ (RU-28965-d₇)is the deuterium labeledRoxithromycin(HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-B0220S

Erythromycin-d6

Erythromycin-d₆ is the deuterium labeled Erythromycin. Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].

HY-B0220S3

Erythromycin-13C2

Erythromycin- ¹³C₂ is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections .

HY-B0905S

Tilmicosin-d3
Tilmicosin-d₃ is the deuterium labeled Tilmicosin. Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.

HY-B0220S1

Erythromycin-13C,d3

Erythromycin- ¹³C,d₃ is the ¹³C- and deuterium labeled Erythromycin. Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].

HY-B0519AS

Tylosin-d3

Tylosin-d₃ is the deuterium labeled Tylosin. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle[1][2][3].

HY-B0220S2

Erythromycin-d3

Erythromycin-d3 is the deuterium labeled Erythromycin[1]. Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research[2][3][4][5].

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